Both CBD and THC are natural compounds that interact with the Endocannabinoid System (ECS), however these two compounds produce very different effects. Read on to learn more.

CBD can be obtained from the Hemp Plant or from the Marijuana Plant, however in the United States it is only legal to extract CBD from the Hemp Plant. In order for the Hemp Plant to constitute as legal in the U.S.A., the plant must contain under 0.3% THC, with the majority of companies trending towards little-to-no THC in their finalized products. CBD today is sold in many different forms including topicals, tinctures, gels, candies, oils, supplements, and more.

THC, on the other hand, is mainly derived from marijuana and it is the chemical responsible for most of marijuana’s psychological effects. Similarly, THC can be found in a variety of products including edibles, capsules, etc. Though both CBD and THC interact with the body’s endocannabinoid system, they both interact with the body in very different ways.

CBD versus THC

Following are some of the significant differences between CBD and THC;

Chemical Structure

CBD and THC have a similar chemical formula; 21 carbon iotas, 30 hydrogen atoms, and two oxygen atoms. The distinction lies in the manner the atoms are arranged. That gives CBD and THC diverse chemical properties, and they influence your body in different ways.  Both CBD and THC effect the CB1 and CB2 receptors in the brain.

Psychoactive components

CBD is non-psychoactive and therefore does get you “high”. CBD influences CB1 and CB2 receptors: 

CB1 Receptors: “CB1 receptors are present throughout the body, but many are in the brain. The CB1 receptors in the brain deal with coordination and movement, pain, emotions, and mood, thinking, appetite, and memories, and other functions. THC attaches to these receptors”.

CB2 Receptors: “CB2 receptors are more common in the immune system. They affect inflammation and pain.”

THC, on the other hand, is the main psychoactive compound in marijuana. It is what makes individuals feel “high.”


In the United States, cannabis-related laws are ever-changing. Before you attempt to purchase items with CBD or THC, get information about your state’s laws.

Medical Advantages

Currently, there is little formal research to support the efficacy of CBD in relation to specific conditions. In June 2018, the Food and Drug Administration endorsed 1 CBD drug; Epidiolex. It is used to treat uncommon, hard to-control types of epilepsy.

Despite a lack of research, many people claim that CBD has helped them. Below are common symptoms that people have mentioned:

  • inflammation
  • nausea
  • depression
  • anxiety

Both CBD and THC are stored in body fat after consumption, therefore CBD may appear on drug tests.



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